Table 1.
Demographic and clinical characteristics of the study sample.
| Demographics | LPA (n = 12) |
SD (n = 11) |
PNFA (n = 9) |
AD (n = 19) |
bvFTD (n = 26) |
Control (n = 31) |
F-Test | Post Hoc |
|---|---|---|---|---|---|---|---|---|
| Age (y) | 69.8 (7.0) | 63.8 (6.2) | 67.1 (6.1) | 66.1 (7.6) | 64.8 (5.8) | 65.4 (6.3) | NS | - |
| Education (y) | 11.9 (3.5) | 13.8 (2.3) | 12.4 (3.2) | 13.2 (3.7) | 12.1 (3.7) | 13.9 (3.7) | NS | - |
| Sex (M:F) | 7:5 | 7:4 | 2:7 | 10:9 | 19:7 | 16:15 | NS | - |
| Disease Duration (y) | 5.2 (2.5) | 6.7 (2.9) | 6.1 (3.0) | 7.2 (5.1) | 7.5 (4.7) | - | NS | - |
| ACE-III Total (100) | 63.7 (17.1) | 71.1 (21.7) | 80.0 (16.1) | 69.6 (12.5) | 82.8 (9.3) | 94.1 (3.8) | *** | CN > Patients |
| FRS (Rasch score) | 0.85 (1.4) | 0.82 (1.4) | 2.7 (1.8) | 0.42 (1.1) | −0.38 (1.3) | - | *** | PNFA > AD, bvFTD |
| ZBI (48) | 13.2 (6.8) | 18.7 (8.7) | 11.4 (6.5) | 15.2 (8.7) | 21.4 (10.0) | - | * | bvFTD > PNFA |
Notes: Means with standard deviations in parentheses. AD = Alzheimer’s disease; bvFTD = behavioural variant of frontotemporal dementia; CN = controls; LPA = logopenic progressive aphasia; PNFA = progressive non-fluent aphasia; (y) = years; ZBI = Zarit Burden Interview. * p < 0.05; *** p < 0.0001; - = not applicable; NS = not significant. Education data available for 28 controls. Disease duration available for 15 AD. ACE-III data available for 29 controls. FRS data available for 14 AD and 20 bvFTD.