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. 2021 Dec 8;1(3):100066. doi: 10.1016/j.xgen.2021.100066
REAGENT or RESOURCE SOURCE IDENTIFIER
Deposited data

UK Biobank, including previously quantified liver fat and liver fat quantified via machine learning 17,80; this paper https://www.ukbiobank.ac.uk/; df-22402
Liver fat common variant genome-wide association study summary statistics This paper https://www.ebi.ac.uk/gwas/ Study: GCST90029073
Liver fat previously quantified in Framingham Heart Study 81, 82, 83 https://www.ncbi.nlm.nih.gov/gap/; Dataset: pht005157.v3.p13
Liver fat previously quantified in Multi-Ethnic Study of Atherosclerosis 84,85 https://www.ncbi.nlm.nih.gov/gap/; Dataset: pht002104.v2.p3

Software and algorithms

BOLT-LMM version 2.3.4 26 https://alkesgroup.broadinstitute.org/BOLT-LMM/BOLT-LMM_manual.html
BOLT-REML in BOLT-LMM version 2.3.4 25 https://alkesgroup.broadinstitute.org/BOLT-LMM/BOLT-LMM_manual.html
R statistical software version 3.5 86 http://www.R-project.org/
Michigan Imputation Server version 1.1 87 http://imputationserver.sph.umich.edu/index.html
Liver fat machine learning algorithm architecture and weights This paper https://github.com/broadinstitute/ml4h (liver_fat_from_mri_ukb in model zoo)
PolyFun version 1.0.0 32 https://github.com/omerwe/polyfun
SuSiE version 0.9.53 88 https://stephenslab.github.io/susie-paper/
Ensembl Variant Effect Predictor (VEP) version 96 89 https://uswest.ensembl.org/info/docs/tools/vep/index.html
LOFTEE 57 https://uswest.ensembl.org/info/docs/tools/vep/index.html
Python 3 90 https://www.python.org/
tensorflow version 2.1 91 https://www.tensorflow.org/
ML4H version 0.0.1 92 https://github.com/broadinstitute/ml4h