Deposited data |
|
UK Biobank, including previously quantified liver fat and liver fat quantified via machine learning |
17,80; this paper |
https://www.ukbiobank.ac.uk/; df-22402 |
Liver fat common variant genome-wide association study summary statistics |
This paper |
https://www.ebi.ac.uk/gwas/ Study: GCST90029073 |
Liver fat previously quantified in Framingham Heart Study |
81, 82, 83
|
https://www.ncbi.nlm.nih.gov/gap/; Dataset: pht005157.v3.p13 |
Liver fat previously quantified in Multi-Ethnic Study of Atherosclerosis |
84,85
|
https://www.ncbi.nlm.nih.gov/gap/; Dataset: pht002104.v2.p3 |
|
Software and algorithms |
|
BOLT-LMM version 2.3.4 |
26 |
https://alkesgroup.broadinstitute.org/BOLT-LMM/BOLT-LMM_manual.html |
BOLT-REML in BOLT-LMM version 2.3.4 |
25 |
https://alkesgroup.broadinstitute.org/BOLT-LMM/BOLT-LMM_manual.html |
R statistical software version 3.5 |
86 |
http://www.R-project.org/ |
Michigan Imputation Server version 1.1 |
87 |
http://imputationserver.sph.umich.edu/index.html |
Liver fat machine learning algorithm architecture and weights |
This paper |
https://github.com/broadinstitute/ml4h (liver_fat_from_mri_ukb in model zoo) |
PolyFun version 1.0.0 |
32 |
https://github.com/omerwe/polyfun |
SuSiE version 0.9.53 |
88 |
https://stephenslab.github.io/susie-paper/ |
Ensembl Variant Effect Predictor (VEP) version 96 |
89 |
https://uswest.ensembl.org/info/docs/tools/vep/index.html |
LOFTEE |
57 |
https://uswest.ensembl.org/info/docs/tools/vep/index.html |
Python 3 |
90 |
https://www.python.org/ |
tensorflow version 2.1 |
91 |
https://www.tensorflow.org/ |
ML4H version 0.0.1 |
92 |
https://github.com/broadinstitute/ml4h |