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. 2021 Dec 17;13(24):6354. doi: 10.3390/cancers13246354

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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PIK3R1 and SFN methylation can predict recurrence in the TCGA pancreatic cancer cohort. Kaplan–Meier curves for recurrence-free survival (RFS) considering the methylation levels of the probes (a) cg15021292 within PIK3R1 and (b–d) cg17330303, cg13466284, and cg12583970 within SFN. The cut-off values and sensitivity and specificity values were, respectively, 0.6473 (75.60% and 87.50%), 0.6973 (75.15% and 87.50%), 0.7923 (80.47% and 87.50%), and 0.7683 (75.15% and 87.50%). Patients with methylation levels inferior and superior to the cut-off were considered as lowly and highly methylated, respectively. HR, hazard ratio.