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. 2021 Dec 7;11(12):1842. doi: 10.3390/biom11121842

Table 4.

Gene sets enriched in the high PLOD2 expression phenotype.

TERM ES NES NOM p-val FDR q-val FWER p-val
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION 0.74 3.51 <0.001 <0.001 <0.001
HALLMARK_UV_RESPONSE_DN 0.62 2.83 <0.001 <0.001 <0.001
HALLMARK_MITOTIC_SPINDLE 0.54 2.55 <0.001 <0.001 <0.001
HALLMARK_G2M_CHECKPOINT 0.52 2.47 <0.001 <0.001 <0.001
HALLMARK_TGF_BETA_SIGNALING 0.61 2.36 <0.001 <0.001 <0.001
HALLMARK_HYPOXIA 0.49 2.31 <0.001 <0.001 <0.001
HALLMARK_ANGIOGENESIS 0.62 2.21 <0.001 <0.001 <0.001
HALLMARK_PROTEIN_SECRETION 0.51 2.19 <0.001 <0.001 <0.001
HALLMARK_HEDGEHOG_SIGNALING 0.6 2.16 <0.001 <0.001 <0.001
HALLMARK_INFLAMMATORY_RESPONSE 0.45 2.13 <0.001 <0.001 <0.001
HALLMARK_E2F_TARGETS 0.44 2.11 <0.001 <0.001 <0.001
HALLMARK_KRAS_SIGNALING_UP 0.44 2.08 <0.001 <0.001 <0.001
HALLMARK_TNFA_SIGNALING_VIA_NFKB 0.42 2.01 <0.001 <0.001 <0.001
HALLMARK_ANDROGEN_RESPONSE 0.46 1.99 <0.001 <0.001 0.001
HALLMARK_IL6_JAK_STAT3_SIGNALING 0.45 1.91 <0.001 <0.001 0.003
HALLMARK_APICAL_JUNCTION 0.4 1.91 <0.001 <0.001 0.003
HALLMARK_GLYCOLYSIS 0.4 1.9 <0.001 <0.001 0.003
HALLMARK_COAGULATION 0.41 1.87 <0.001 <0.001 0.004
HALLMARK_IL2_STAT5_SIGNALING 0.36 1.7 <0.001 0.002 0.035
HALLMARK_COMPLEMENT 0.35 1.66 <0.001 0.003 0.054

ES, Enrichment score; NES, Normalized Enrichment Score; NOM p-val, Nominal p Value; FDR q-val, False Discovery Rate q Value; FWER p-val, Family-wise Error Rate p Value.