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Growth profiles of murine fibroblast 10T1/2 cells: (a) Glucose oxidase (GOD) or (b) choline oxidase (COD) was included in the medium during the first 24 h at concentrations shown in each panel. Control: cultured in a medium free of GOD and COD. Morphology of 10T1/2 cells at 40 h: (c) control, (d) with 2.5 U/mL GOD as shown in panel (a), and (e) with 2.5 U/mL COD as shown in panel (b). Bars in panels (a,b): standard deviation (n = 3), and in panels (c–e): 200 µm.
