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. 2021 Dec 10;11(12):1855. doi: 10.3390/biom11121855

Figure 3.

Figure 3

Structural assembly and functional characterization of tetrahedral DNA. (a) Laser scanning confocal microscopy (LSCM) was used to observe the uptake of L-DNA tetrahedrons (L-TDs) of different sizes by living cells over time and to test the potential of L-TDs to deliver low-dose Dox in mice, reproduced with permission from Reference [59], Copyright 2017 Elsevier. (b) AS1411 aptamers are attached to multiple overhangs on the tetrahedral edge of DNA to target nucleolin receptors on the plasma membrane of cancer cells, reproduced with permission from Reference [67], Copyright 2014 American Chemical Society.