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. 2021 Nov 25;11(12):478. doi: 10.3390/bios11120478

Table 1.

Limit, sources, and effects of various heavy metal ion contaminations. Reprinted from [3], Copyright 2015, with permission from Elsevier.

Metals WHO Limit a (mgL−1) Common Sources Effects
Lead (Pb) 0.05 PVC pipes in sanitation, agriculture, recycled PVC lead paints, jewellery, lead batteries, lunch boxes, etc. Penetrates through protective blood brain barrier (BBB) and is proving to be a risk factor for Alzheimer’s disease and senile dementia; leads also to neuro-degenerative diseases, decreases IQ, kidney damage, decreased bone growth, behavioral issues, ataxia, hyperirritability and stupor
Cadmium (Cd) 0.005 Paints, pigments, electroplated parts, batteries, plastics, synthetic rubber, photographic and engraving process, photoconductors and photovoltaic cells Renal toxicity, hypertension, weight loss, fatigue, microcytic hypochromic anaemia, lymphocytosis, pulmonary fibrosis, atherosclerosis, peripheral neuropathy, lung cancer, osteomalacia, osteoporosis and hyperuricemia
Mercury (Hg) 0.001 Combustion of coal, municipal solid waste incineration and volcanic emissions Impaired neurologic development, effects on digestive system, immune system, lungs, kidneys, skin and eyes, minamata, acrodynia, increases salivation, hypotonia and hypertension
Arsenic (As) 0.05 Wooden electricity poles that are treated with arsenic based preservatives, pesticides, fertilizers, release of untreated effluents, oxidation of pyrite (FeS) and arseno pyrite (FeAsS) Causes effects on central nervous system (CNS), peripheral nervous system (PNS), cardiovascular, pulmonary diseases, gastrointestinal tract (GI), genitourinary (GU), haemopoietic, dermatologic, foetal and teratogenic diseases, anorexia, brown pigmentation, hyper-pigmentation, localized edema and skin cancer
Chromium (Cr) 0.05 Leather industry, tanning, and chrome plating industries Reproductive toxicity, embryotoxicity, teratogenicity, mutagenicity, carcinogenicity, lung cancer, dermatitis, skin ulcers, perforation of septum and irritant contact dermatitis
Silver (Ag) 0.1 Refining of copper, gold, nickel, zinc, jewellery and electroplating industries Argyria, gastroenteritis, neuronal disorders, mental fatigue, rheumatism, knotting of cartilage, cytopathological effects in fibroblast, keratinocytes and mast cells
Zinc (Zn) 5 Soldering, cosmetics and pigments Respiratory disorders, metal fume fever, bronchiolar leukocytes, neuronal disorder, prostate cancer risks, macular degeneration and impotence
Copper (Cu) 1.3 Fertilizers, tanning and photovoltaic cells Adreno-corticol hyperactivity, allergies, anaemia, alopecia, arthritis, autism, cystic fibrosis, diabetes, haemorrhaging and kidney disorders

a World Health Organization (WHO) tolerable limits for heavy metal ions in water.