Table 2.
Treatment-related toxicities.
| Toxicity | Grade 1 | Grade 2 | Grade 3 | Total (N = 44) |
|---|---|---|---|---|
| Pain | 2 | 42 | 0 | 44 |
| Nausea | 4 | 0 | 0 | 4 |
| Vomiting | 5 | 5 | 0 | 10 |
| Urticaria | 0 | 18 | 0 | 18 |
| Pruritus | 1 | 19 | 0 | 20 |
| Flushing | 3 | 7 | 0 | 10 |
| Cough | 2 | 0 | 0 | 2 |
| Edema | 1 | 3 | 0 | 4 |
| Fatigue | 0 | 2 | 0 | 2 |
| Fever | 1 | 0 | 0 | 1 |
| Elevated AST | 20 | 4 | 1* | 25 |
| Elevated ALT | 16 | 7 | 1* | 25 |
| Hypertension | 3 | 0 | 0 | 3 |
| Anxiety/agitation | 4 | 0 | 0 | 4 |
Only toxicity related to BG (recorded as DLT in one patient). All other toxicities were expected and related to 3F8. Abbreviations: AST, aspartate aminotransferase; ALT, alanine aminotransferase.