PC |
Pancreatic cancer |
siRNA |
Small interfering RNA |
BBB |
Blood-brain barrier |
BTB |
Blood-tumor barrier |
RNAi |
RNA interference |
mRNA |
Messenger RNA |
RISC |
RNA-induced silencing |
Ago |
Argonaute |
HSP27 |
Heat shock protein 27 |
PARP |
Poly (ADP-ribose) polymerase |
ESM-1 |
Endothelial cell-specific molecule-1 |
proNGF |
Precursor of nerve growth factor |
ATG5 |
Autophagy-related gene 5 |
RAP80 |
Receptor-associated protein 80 |
HIF-1α |
Hypoxia inducible factor-1α |
NF-κB |
Nuclear factor-kappaB |
COX-2 |
Cyclooxygenase-2 |
EGFR |
Epidermal growth factor receptor |
VEGF |
Vascular endothelial growth factor |
HDAC |
Histone deacetylase |
HRE |
Hypoxia response element |
HPA |
Heparinase |
FGF2 |
Fibroblast growth factor 2 |
SDC1 |
Syndecan-1 |
EMT |
Epithelial-to-mesenchymal transition |
NELFE |
Negative elongation factor E |
NDRG2 |
N-Myc downstream-regulated gene 2 |
lncRNA |
long non-coding RNA |
miRNA |
microRNA |
MMP |
Matrix metalloproteinase |
TGF-β |
Transforming growth factor-beta |
RIG-I |
Retinoic acid-inducible gene I |
CADM1 |
Cell adhesion molecule 1 |
RR |
Ribonucleotide reductase |
DOX |
Doxorubicin |
GEM |
Gemcitabine |
hTERT |
Human telomerase reverse transcriptase |
hnRNP |
Heterogenous nuclear ribonucleotide protein A2/B1 |
TS |
Thymidylate synthase |
TRAIL |
TNF-related apoptosis-inducing ligand |
Mcl-1 |
Myeloid cell leukemia 1 |
EPR |
Enhanced permeability and retention |
Fab |
Fragment |
PIC |
Polyion complex |
TF |
Tissue factor |
BCPVs |
Biodegradable charged polyester-based vectors |
iRGD |
Internalizing RGD peptide |
IV |
Intravenous |
EPAS1 |
Endothelial PAS domain protein 1 |
PLGA |
Polyethylenimine-poly (lactic-coglycolide) |
GPCR |
G protein-coupled receptor |
ABC |
ATP-binding cassette |
YAP |
Yes-associated protein |
LODER |
Local drug EluteR |
2D |
Two-dimensional |
PEG |
Polyethylene glycol |
PTX |
Paclitaxel |
PTP |
Plectin-1 targeted peptide |
SPIONs |
Superparamagnetic iron oxide nanoparticles |
PLK1 |
Polo-like kinase 1 |
NGF |
Nerve growth factor |
PI3K |
Phosphoinositide 3-kinase |
Akt |
Protein kinase-B |
MSNPs |
Mesoporous silica nanoparticles |
PEI |
Polyethyleneimine |