Table 1.
Participant Characteristic | Matched Case-Control Pairs | Follow-Up Sample (n = 1088) |
|
---|---|---|---|
Cases of Overall Cancer (n = 3481) |
Controls (n = 3481) |
||
Age at blood draw, median [IQR] | 60.8 [54.1–65.9] | 60.8 [53.9–65.6] | 69.9 [62.8–75.6] |
Sex: | |||
Male, n (%) | 2125 (61%) | 2125 (61%) | 740 (68%) |
Female, n (%) | 1356 (39%) | 1356 (39%) | 348 (32%) |
Country of birth: | |||
Australia/New-Zealand, n (%) | 2380 (68%) | 2367 (68%) | 831 (77%) |
Greece, n (%) | 350 (10%) | 361 (10%) | 44 (4%) |
Italy, n (%) | 520 (15%) | 520 (15%) | 89 (8%) |
UK/other, n (%) | 231 (7%) | 233 (7%) | 124 (11%) |
Blood sample type: | |||
Dried blood spots, n (%) | 2412 (69%) | 2412 (69%) | |
Peripheral blood mononuclear cells, n (%) | 873 (25%) | 873 (25%) | 1088 (100%) |
Buffy coats, n (%) | 196 (6%) | 196 (6%) | |
Smoking status: | |||
Current, n (%) | 490 (14%) | 472 (14%) | 62 (6%) |
Former, n (%) | 1377 (40%) | 1337 (38%) | 478 (44%) |
Never, n (%) | 1613 (46%) | 1671 (48%) | 548 (50%) |
Smoking pack-years, median [IQR] | 1.6 [0–28.5] | 0.75 [0–25.7] | - |
Body mass index (kg/m2), median [IQR] | 26.8 [24.4–29.6] | 26.7 [24.4–29.3] | 26.8 [24.2–29.4] |
Alcohol consumption a (g/day), median [IQR] | 4.3 [0–17.7] | 4.3 [0–17.0] | 8.8 [0–23.0] |
a Alcohol consumption was reported for the past week at baseline and in the past 12 months at follow-up.