Table 2.
Specificity of epigenetic drugs discussed throughout this review article.
| Inhibitor | Target |
|---|---|
| AR42 | All HDACs |
| Trichostatin A (TSA) | All HDACs |
| Valproic acid | HDAC1 |
| Panobinostat | All HDACs |
| Vorinostat (SAHA) | All HDACs |
| Mocetinostat | HDAC1, HDAC2, HDAC3, HDAC11 |
| ACY-1215 | HDAC1, HDAC2, HDAC3, HDAC6, HDAC8 |
| Entinostat | HDAC1, HDAC3 |
| Romidepsin | HDAC1, HDAC2 |
| Tubastatin | HDAC6 |
| PCI-34051 | HDAC8 |
| ACY-241 | HDAC1, HDAC2, HDAC3, HDAC6, HDAC8 |
| Nexturastat A | HDAC6 |
| Suprastat | HDAC6 |
| Decitabine (5-aza-2′-deoxycytidine) | DNMTs |
| Guadecitabine | DNMTs |
HDAC (histone deacetylase); SAHA (suberoylanilide hydroxamic acid); DNMT (DNA methyltransferase). This table was adapted from Banik et al. [18].