Table A4.

Treatment effect parameters for individual DMTs.

Treatment	Relative Risk EDSS Progression (Range)	Rate Ratio for Relapse Rate (Range)
Alemtuzumab	0.25–0.68	0.22–0.35
Dimethyl Fumarate	0.46–0.84	0.43–0.63
Fingolimod	0.51–0.90	0.39–0.55
Glatiramer acetate 20 mg	0.58–0.94	0.55–0.71
Interferon β-1a 30 mcg	0.63–1.00	0.74–0.94
Interferon β-1a 22 mcg	0.52–1.23	0.55–0.85
Interferon β-1a 44 mcg	0.52–0.99	0.54–0.73
Interferon β-1b 250 mcg	0.46–0.89	0.55–0.77
Natalizumab	0.37–0.84	0.25–0.40
Ocrelizumab	0.28–0.76	0.27–0.44
Peginterferon β-1a	0.37–1.02	0.47–0.86
Teriflunomide 7 mg	0.63–1.14	0.67–0.93
Teriflunomide 14 mg	0.52–0.97	0.56–0.79

Source: adapted from ([17] Appendix Table E7).