Table 6. Association between psychosocial stress and composite neuroendocrine biomarker index among monoracial non-Hispanic Black women overall and by HIV serostatus (n = 48).
Unadjusted model | Full model a | Parsimonious Model b | ||||
---|---|---|---|---|---|---|
β (95% CI) | p | β (95% CI) | p | β (95% CI) | p | |
Overall (n = 48) | ||||||
Psychosocial stress latent profile membership | ||||||
Low | ref | ref | ref | |||
Moderate | 0.53 (-0.06, 1.13) | 0.078 | 0.30 (-0.42, 1.03) | 0.40 | 0.33 (-0.24, 0.90) | 0.25 |
High | 0.73 (-0.11, 1.57) | 0.088 | 1.32 (0.20, 2.43) | 0.022 | 1.31 (0.41, 2.21) | 0.0053 |
Among WLWH (n = 31) | ||||||
Psychosocial stress latent profile membership | ||||||
Low | ref | ref | ref | |||
Moderate | 0.37 (-0.35, 1.09) | 0.30 | 0.13 (-1.41, 1.68) | 0.86 | 0.06 (-0.76, 0.88) | 0.88 |
High | 0.98 (0.01, 1.96) | 0.049 | 1.93 (0.02, 3.83) | 0.048 | 1.64 (0.54, 2.73) | 0.0052 |
Among HIV-negative women (n = 17) | ||||||
Psychosocial stress latent profile membership | ||||||
Low | ref | ref | ref | |||
Moderate | 0.72 (-0.37, 1.81) | 0.18 | 0.36 (-0.66, 1.38) | 0.38 | 0.32 (-0.41, 1.06) | 0.32 |
High | 0.17 (-1.52, 1.86) | 0.84 | 2.54 (0.41, 4.67) | 0.030 | 2.51 (0.93, 4.08) | 0.0080 |
Abbreviations: CI, confidence interval; WLWH, women living with HIV; ref, reference group.
Bolded numeric values indicate p<0.05.
a Adjusted for HIV status (only in the overall sample), age, education at study entry, income, current smoking, alcohol use, recent substance use, use of a prescribed psychotropic medication, body mass index, menopausal status, CD4+ T cell count (only among WLWH), and HIV viral load (only among WLWH).
b In the overall sample, adjusted for HIV status, age, income, alcohol use, recent substance use, and body mass index. Among WLWH, adjusted for age, recent substance use, use of a prescribed psychotropic medication, and HIV viral load. Among HIV-negative women, adjusted for age, education at study entry, current smoking, alcohol use, recent substance use, body mass index, and menopausal status.