Table 1.

Examples of studies involving NOX and ER stress crosstalk in different tissues.

NOX Influence on ER Stress	Model	Details	Ref
NOX inhibition → ER stress inhibition	Cardiomyocytes	NOX inhibition with apocynin or Rac1 KO mice	[184]
NOX inhibition → ER stress inhibition	Macrophages	NOX2 siRNA or NOX2 KO mice	[185]
NOX inhibition → ER stress inhibition	Neutrophils	HL60 cell line; NOX inhibition with DPI	[186]
NOX activation → ER stress activation	Neutrophils	HL60 cell line; NOX activation with PMA	[186]
NOX inhibition → no effect in ER stress	Mice islets	NOX inhibition with VAS2870	[144]
ER Stress Influence on NOX	Model	Details	Ref
ER stress induction → NOX increased expression	Macrophages	ER stress induction by cholesterol or 7-ketocholesterol	[185]
ER stress attenuation → NOX inhibition	Mice islets	ER stress attenuation with 4-PBA; NOX2-derived H2O2 peak was delayed	[189]