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. 2021 Dec 8;11(12):1617. doi: 10.3390/brainsci11121617

Figure 5.

Figure 5

Effect of clobenpropit (CLO) on mitochondrial respiratory chain complex (MRCC) (A) MRCC-I, (B) MRCC-II, and (C) MRCC-IV activities in lipopolysaccharides (LPS)-treated mice brains. LPS-CLO-1 and LPS-CLO-3 refer to the administration of clobenpropit (1 or 3 mg/kg, p.o., respectively) and lipopolysaccharides (250 μg/kg, i.p.). MRCC levels were decreased with administration of LPS injection and the levels were increased with oral administration of CLO. The results are expressed as mean ± SEM (n = 6). One-way ANOVA (F(3,20) = 10.76, p < 0.001 for MRCC-I; F(3,20) = 4.270, p < 0.05 for MRCC-II; F(3,20) = 16.85, p < 0.001 for MRCC-IV) was followed by Tukey–Kramer multiple comparisons tests. * p < 0.05, ** p < 0.01 and *** p < 0.001 as compared to the control group; ns, not significant as compared to the control group; # p < 0.05 and ### p <0.001 as compared to the LPS-treated group.