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. 2021 Nov 30;10(12):3370. doi: 10.3390/cells10123370
CACNA1C/D/G calcium voltage-gated channel subunit alpha1 C/D/G
CaV1.2/1.3 voltage-gated L-type calcium channel subunit alpha 1.2/1.3
CaV3.1 voltage-gated T-type calcium channel subunit alpha 3.1
cDNA complementary deoxyribonucleic acid
CiPA Comprehensive in vitro Proarrhythmia Assay
DNA deoxyribonucleic acid
CT cycle threshold
ΔCT normalized cycle threshold
D-PBS Dulbecco´s phosphate buffered saline
EC solution extracellular solution
GAPDH glyceraldehyde-3-phosphate dehydrogenase
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
hERG channel human ether-a-go-go related gene channel
hiPSC-CM human induced pluripotent stem cell derived cardiomyocytes
IC solution intracellular solution
ICaL L-type calcium current
ICaT T-type calcium current
If funny current
IK1 inward rectifier potassium current
IKr rapid component of the delayed rectifier potassium current
IKur ultra-rapid delayed rectifier potassium current
INa cardiac sodium current
KCNA5 potassium voltage-gated channel subfamily A member 5
KCNH2 potassium voltage-gated channel subfamily H member 2
KCNJ2/4 potassium inwardly rectifying channel subfamily J member 2/4
Kir2.1/2.3 inward-rectifier potassium ion channel subunit 2.1/2.3
KV 1.5/1.11 voltage-gated potassium channel subunit 1.5/1.11
mRNA messenger ribonucleic acid
RNA ribonucleic acid
RNase ribonuclease
rt room temperature
RT reverse transcription
SCN5A sodium voltage-gated channel alpha subunit 5
SD standard deviation
RT-qPCR reverse transcription quantitative polymerase chain reaction
TdP Torsade de Pointes
TNNT2 troponin T2, cardiac type
TTX tetrodotoxin