CACNA1C/D/G |
calcium voltage-gated channel subunit alpha1 C/D/G |
CaV1.2/1.3 |
voltage-gated L-type calcium channel subunit alpha 1.2/1.3 |
CaV3.1 |
voltage-gated T-type calcium channel subunit alpha 3.1 |
cDNA |
complementary deoxyribonucleic acid |
CiPA |
Comprehensive in vitro Proarrhythmia Assay |
DNA |
deoxyribonucleic acid |
CT |
cycle threshold |
ΔCT |
normalized cycle threshold |
D-PBS |
Dulbecco´s phosphate buffered saline |
EC solution |
extracellular solution |
GAPDH |
glyceraldehyde-3-phosphate dehydrogenase |
HCN4 |
hyperpolarization activated cyclic nucleotide gated potassium channel 4 |
hERG channel |
human ether-a-go-go related gene channel |
hiPSC-CM |
human induced pluripotent stem cell derived cardiomyocytes |
IC solution |
intracellular solution |
ICaL
|
L-type calcium current |
ICaT
|
T-type calcium current |
If
|
funny current |
IK1
|
inward rectifier potassium current |
IKr
|
rapid component of the delayed rectifier potassium current |
IKur
|
ultra-rapid delayed rectifier potassium current |
INa
|
cardiac sodium current |
KCNA5 |
potassium voltage-gated channel subfamily A member 5 |
KCNH2 |
potassium voltage-gated channel subfamily H member 2 |
KCNJ2/4 |
potassium inwardly rectifying channel subfamily J member 2/4 |
Kir2.1/2.3 |
inward-rectifier potassium ion channel subunit 2.1/2.3 |
KV 1.5/1.11 |
voltage-gated potassium channel subunit 1.5/1.11 |
mRNA |
messenger ribonucleic acid |
RNA |
ribonucleic acid |
RNase |
ribonuclease |
rt |
room temperature |
RT |
reverse transcription |
SCN5A |
sodium voltage-gated channel alpha subunit 5 |
SD |
standard deviation |
RT-qPCR |
reverse transcription quantitative polymerase chain reaction |
TdP |
Torsade de Pointes |
TNNT2 |
troponin T2, cardiac type |
TTX |
tetrodotoxin |