Table 2.
Vitamin D 5000 IU + Standard Treatment (n=34) | Standard Treatment (n=34) | Overall (n=68) | p-valuea | |
---|---|---|---|---|
Visual analog scale (0–10) | ||||
Baseline | 5.74 ± 2.16 | 5.46 ± 2.13 | 5.60 ± 2.13 | 0.560 |
Week 4 | 3.76 ± 2.32 | 3.81 ± 2.47 | 3.79 ± 2.38 | 0.946 |
Week 8 | 2.39 ± 2.09 | 3.09 ± 2.33 | 2.74 ± 2.22 | 0.221 |
Changes from baseline to week 8 | −3.34 ± 2.03 | −2.37 ± 2.2 | −2.85 ± 2.16 | 0.044* |
p-valueb | <0.001* | <0.001* | <0.001* | |
Burning pain (0–100) | ||||
Baseline | 11.76 ± 23.8 | 17.06 ± 25.88 | 14.41 ± 24.82 | 0.384 |
Week 4 | 4.18 ± 11.84 | 9.41 ± 17.22 | 6.76 ± 14.91 | 0.189 |
Week 8 | 1.76 ± 7.16 | 6.18 ± 13.93 | 3.97 ± 11.21 | 0.046* |
Changes from baseline to week 8 | −10 ± 20.15 | −10.89 ± 25.51 | −10.44 ± 22.82 | 0.859 |
p-value | 0.007* | 0.023* | 0.001* | |
Electric shocks pain (0–100) | ||||
Baseline | 10.29 ± 21.39 | 22.35 ± 27.64 | 16.32 ± 25.27 | 0.057 |
Week 4 | 6.47 ± 17.21 | 12.35 ± 20.75 | 9.41 ± 19.15 | 0.110 |
Week 8 | 4.71 ± 13.54 | 6.76 ± 13.64 | 5.74 ± 13.63 | 0.482 |
Changes from baseline to week 8 | −5.59 ± 12.36 | −15.59 ± 23.77 | −10.59 ± 19.46 | 0.070 |
p-valueb | 0.011* | 0.001* | <0.001* | |
Tingling (0–100) | ||||
Baseline | 30.88 ± 29.27 | 36.18 ± 30.85 | 33.53 ± 29.96 | 0.483 |
Week 4 | 17.94 ± 22.8 | 25.29 ± 27.55 | 21.62 ± 25.37 | 0.242 |
Week 8 | 10.59 ± 18.9 | 20.29 ± 26.91 | 15.44 ± 23.59 | 0.096 |
Changes from baseline to week 8 | −20.29 ± 23.29 | −15.88 ± 21.62 | −18.09 ± 22.41 | 0.415 |
p-valueb | <0.001* | <0.001* | <0.001* | |
Numbness (0–100) | ||||
Baseline | 43.53 ± 31.13 | 41.76 ± 25.76 | 42.65 ± 28.37 | 0.719 |
Week 4 | 29.41 ± 29.23 | 30.88 ± 27.34 | 30.15 ± 27.34 | 0.750 |
Week 8 | 20.59 ± 25.93 | 26.47 ± 26.73 | 23.53 ± 26.30 | 0.257 |
Changes from baseline to week 8 | −22.94 ± 24.93 | −15.29 ± 18.13 | −19.12 ± 21.97 | 0.373 |
p-valueb | <0.001* | <0.001* | <0.001* |
Notes: Data are presented as mean ± standard deviation (SD); aComparison between the experimental and control group; bComparison within-group under the same conditions; *p-value is statistically significant.