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Examples of two invasive ductal carcinomas that were ER, PR, and HER-2 negative (a,c). The SP142 diagnostic assay yielded positive results for PD-L1 status, defined as ≥1% IC staining (PD-L1 expression on tumor-infiltrating immune cells as a percentage of tumor area) in the first patient (b) and negative results in the second patient (d).
