Table 1.
Gadopentetate Dimeglumine (Magnevist®) | Gadobutrol (Gadovist®) | |
---|---|---|
Chemical Structures |
![]() Gd-DTPA (Linear chelate) |
![]() Gd-BT-DO3A (Macrocyclic chelate) |
Molecular weight | 938 g/mol | 604.71 g/mol |
Ionic charge | divalent ionic | non-ionic |
Concentration | 0.5 M | 1.0 M |
Osmolality | 1960 | 1603 |
Excess ligand | 0.4 mg/mL | - |
log Ktherm | 22.5 | 21.8 |
log Kcond | 18.4 | 14.7 |
Kinetic stability | Low | High |