Table 2.

Descriptive statistics for the LDL concentration, HDL concentration, oxidized LDL concentration, monocyte cell concentration, macrophage cell concentration, synthetic SMC concentration, collagen concentration, cytokine concentration, foam cell concentration, plaque volume and area of simulated thickened wall for the normal, overestimated and underestimated geometries, respectively. The relative error and uncertainty are also presented. The relative error is defined as the percentage difference between the two models (over and underestimated).

	Minimum	Maximum	Mean	Std. Deviation	Relative Error Minimum	Relative Error Maximum	Relative Error Mean	Uncertainty
Shear stress	0.577	24.1	2.5663	1.8863
Overestimated	0.495	23	2.3938	1.7576	−14.2	−4.56	−6.72	1.7599
Underestimated	0.63	25.7	2.7163	1.9902	9.19	6.64	5.84	1.9922
Thickened Wall	2.55 × 10−6	2.70 × 10−5	1.23 × 10−5	5.38 × 10−6
Overestimated	2.68 × 10−6	2.84 × 10−5	1.27 × 10−5	5.49 × 10−6	5.10	5.19	2.74	1.7599
Underestimated	2.44 × 10−6	2.84 × 10−5	1.20 × 10−5	5.35 × 10−6	−4.31	5.19	−2.81	1.9922
LDL concentration	5.54 × 10−5	6.64 × 10−4	2.27 × 10−4	1.35 × 10−4
Overestimated	5.54 × 10−5	6.54 × 10−4	2.22 × 10−4	1.33 × 10−4	0.00	−1.51	−1.85	1.7599
Underestimated	3.62 × 10−5	6.70 × 10−4	1.80 × 10−4	1.55 × 10−4	−34.7	0.90	−20.5	1.9922
HDL concentration	6.69 × 10−4	8.06 × 10−4	7.45 × 10−4	3.68 × 10−5
Overestimated	6.69 × 10−4	8.08 × 10−4	7.45 × 10−4	3.70 × 10−5	0.00	0.25	5.02 × 10−2	1.7599
Underestimated	2.41 × 10−4	1.79 × 10−3	1.02 × 10−3	4.84 × 10−4	−64.0	1.22 × 102	38.3	1.9922
Oxidized LDL concentration	8.20 × 10−4	1.41 × 10−3	1.16 × 10−3	1.81 × 10−4
Overestimated	8.30 × 10−4	1.41 × 10−3	1.17 × 10−3	1.81 × 10−4	1.22	0.00	0.36	1.7599
Underestimated	7.68 × 10−4	1.45 × 10−3	1.16 × 10−3	2.38 × 10−4	−6.34	2.84	−0.73	1.9922
Monocyte cells concentration	1.32 × 10−7	1.40 × 109	4.13 × 108	2.59 × 108
Overestimated	1.32 × 10−7	1.41 × 109	4.09 × 108	2.57 × 108	0.00	0.71	−0.93	2.57 × 108
Underestimated	1.47 × 10−7	1.37 × 109	4.13 × 108	2.74 × 108	11.4	−2.14	−9.77 × 10−2	2.74 × 108
Macrophage cells concentration	3.40 × 109	2.65 × 1011	8.85 × 1010	5.59 × 1010
Overestimated	3.40 × 109	2.62 × 1011	8.76 × 1010	5.53 × 1010	0.00	−1.13	−0.98	5.53 × 1010
Underestimated	3.55 × 109	3.02 × 1011	8.81 × 1010	5.91 × 1010	4.41	14.0	−0.36	5.91 × 1010
Synthetic SMC concentration	1.00 × 10−18	4.83 × 105	5.79 × 104	9.01 × 104
Overestimated	1.00 × 10−18	4.80 × 105	5.76 × 104	8.90 × 104	0.00	−0.62	−0.65	89073.87
Underestimated	1.01 × 10−18	8.19 × 105	1.74 × 105	1.56 × 105	1.00	69.6	2.01 × 102	155950.1
Collagen concentration	5.60 × 10−26	2.67 × 10−2	3.20 × 10−3	4.98 × 10−3
Overestimated	5.60 × 10−26	2.65 × 10−2	3.18 × 10−3	4.92 × 10−3	0.00	−0.75	−0.69	1.7599
Underestimated	5.65 × 10−26	4.53 × 10−2	9.64 × 10−3	8.62 × 10−3	0.89	0.69	2.01 × 102	1.9922
Cytokine concentration	6.00 × 10−2	1.00 × 101	2.79	1.92
Overestimated	5.99 × 10−2	1.01 × 101	2.77	1.89	−0.17	1.00	−0.99	2.5852
Underestimated	6.70 × 10−2	1.49 × 101	3.48	2.84	11.7	0.49	24.5	3.4721
Foam cells concentration	2.61 × 106	4.88 × 108	1.44 × 108	1.02 × 108
Overestimated	2.61 × 106	4.93 × 108	1.42 × 108	1.00 × 108	0.00	1.02	−1.03	1.01 × 108
Underestimated	2.92 × 106	8.12 × 108	1.79 × 108	1.53 × 108	11.9	66.4	25.1	1.53 × 108
Plaque volume	4.54 × 1017	8.46 × 1019	2.49 × 1019	1.77 × 1019
Overestimated	4.53 × 1017	8.55 × 1019	2.47 × 1019	1.75 × 1019	−0.17	1.01	−1.03	1.75 × 1019
Underestimated	5.07 × 1017	1.41 × 1020	3.12 × 1019	2.66 × 1019	11.7	66.6	25.1	2.66 × 1019