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Summary of the strategies for generating hiPSC for heart disease modeling and protocols to improve the maturation of hiPSC-derived-CMs. Abbreviation: Clustered Regular Interspaced Short Palindromic Repeats-associated Cas9 nuclease, (CRISPR/Cas9); transcription activator-like effector nucleases (TALENs); Zinc finger nucleases, (ZFNs).
