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. 2021 Dec 13;17(12):e1010138. doi: 10.1371/journal.ppat.1010138

Fig 7. Late domain motifs encoded in TgGRA14 C-terminus can mediate ESCRT-dependent HIV virus-like particle release.

Fig 7

A. Schematic of the generation of mutants in the late domain motifs PTAP and YPX(n)L encoded by TgGRA14. B. Analysis of virus-like particle release by GagGRA14 and GagGRA14 mutants. Representative immunoblots of VLP release include top: VLP release sample (100%) and bottom: cellular lysate sample (4%). Data represents the mean from ≥ 6 biological replicates. Statistical analysis was by Student’s t-test. Only statistical differences are shown. *p<0.05, **p<0.01, ***p<0.001.