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. 2021 Nov 27;8(12):1095. doi: 10.3390/children8121095

Table 4.

Concordance rates of causes of deaths between complete diagnostic autopsy and Minimally Invasive Tissue Sampling (MITS) based on histological investigations among all, stillbirths and neonates.

Cause of Death in Complete Diagnostic Autopsy, ICD-10 Code MITS Concordance
All, n = 24 Stillbirths, n = 15 Neonates, n = 9
Intrauterine hypoxia,% (Cohen’s kappa) 100 (1.0) * 100 (1.0) * -
P20.0 Intrauterine hypoxia first noted before onset of labor, % 100 100 -
P20.1 Intrauterine hypoxia first noted during labor and delivery, % 100 100 -
P28.0 Primary atelectasis of newborn 0 - 0
P36.8 Other bacterial sepsis of newborn, % 33.3 - 33.3
E72.2 Disorders of urea cycle metabolism, % 0 - 0
J16.8 Pneumonia due to other specified infectious organisms 100 - 100
Congenital malformations, deformations and chromosomal abnormalities, % (Cohen’s kappa) 0 (0) # 0 (0) # 0 (0) #
Q89.7 Multiple congenital malformations, not elsewhere classified, % 0 0 0
Q91.0 Trisomy 18, meiotic nondisjunction 0 - 0
Overall, % 62.5 86.7 22.2

* McNemar’s test statistic is non-significant and Cohen’s kappa test statistic is statistically significant. # McNemar’s test statistic is statistically significant and Cohen’s kappa test statistic is non-significant.