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Lymphoplasmacytic lymphoma. (A) Splenic lymphopasmacytic lymphoma showing disrupted architecture, H&E, 20×; (B) Focally showing a more diffuse pattern, H&E, 20×; (C) Lymphocytes with a plasmacytic appearance, H&E, 200×; (D) Immunohistochemistry (IHC) for CD138 is positive; (E) IHC is positive for CD20; (F) IHC for kappa is positive, lambda (in set) is negative.
