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. 2021 Dec 16;11(12):2375. doi: 10.3390/diagnostics11122375

Table 3.

Concordance of plasma RAS testing between NGS and BEAMing dPCR (n = 61).

Plasma ctDNA RAS Status by dPCR
RAS Mutant WT Total PPA NPA OPA
Plasma ctDNA RAS status by NGS Mutant 26 1 27 100 × 26/35 = 74.3% 100 × 25/26 = 96.2% 100 × 51/61 = 83.6%
WT 9 25 34
Total 35 26 61

ctDNA: circulating tumor DNA; dPCR: digital PCR; NGS: Next-generation sequencing; WT: Wild type; PPA: Positive percent agreement; NPA: Negative percent agreement; OPA: Overall percent agreement.