Figure 4.

Interaction network of DEG NPC, associated with significantly enriched GO BP terms from groups I and II and diseases and metabolic processes, identified using key words “Parkinson”, “neurodegeneration”, “transport”, “vesicular”, “mitochondria”, “lysosome”, “oxidative stress”, “apoptosis” and “autophagy” based on Pathway Studio data. Genes, overexpressed in NPC derived from twins with PD, as compared to NPC derived from healthy twins are highlighted red. Genes, underexpressed in NPC derived from twins with PD, as compared to NPC derived from healthy twins are highlighted green.