ATP	Adenosine triphosphate
BBB	Blood-brain barrier
CNS	Central nervous system
COX2	Cyclooxygenases 2
DDR	DNA damage response
DSBs	DNA double-strand breaks
DAMP	Damage-associated molecular pattern
ER	Endoplasmic reticulum
ETC	Electron transport chain
GFAP	Glial fibrillary acidic protein
H2O	Water molecules
HMGB1	High-mobility group box 1
IKB	Inhibitory protein
iNOS	Inducible nitric oxide synthase
IR	Ionizing radiation
KLF6	Kruppel like factor 6
5-LPO	5-lypoxygenase
MMPs	Matrix metalloproteinases
mtDNA	Mitochondrial DNA
NADH	Nicotinamide adenine dinucleotide
NO	Nitric oxide
NF-κB	Nuclear factor kappa B
Nrf2	Nuclear factor E2-related factor 2
O2−	Superoxide anion
PGH2	Prostaglandin H 2
RNS	Reactive nitrogen species
ROS	Reactive oxygen species
SASP	Senescence associated secretion phenotype
SA-β-Gal	Senescence-associated-β-galactosidase
SIPS	Stress-induced premature senescence
TLR4	Toll-like receptor 4
TLRs	Toll-like receptors
TNF-α	Tumor necrosis factor-α