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. 2021 Dec 20;10(12):3595. doi: 10.3390/cells10123595

Figure 4.

Figure 4

Functional analyses of the control and PAH iPSC-CM monolayers under spontaneous beating conditions. (AC) Beating frequency (beats per minute, bpm), contraction time (s), and relaxation time (s) in the control and PAH iPSC-CMs (mean + SD, N = 46 control wells from seven different cardio-differentiations, and N = 16 PAH wells from five different cardio-differentiations). (DF) Functional response of the control and PAH iPSC-CMs to increasing isoprenaline concentrations (nM) overtime (mean ± SD, N = 15 control, and N = 8 PAH). * p < 0.05, ** p < 0.01.