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. 2021 Dec 10;10(12):3489. doi: 10.3390/cells10123489

Table 4.

Genotype and allele frequencies of the HPSE gene SNPs in CMV seropositive patients with hematological malignancies.

SNP Genotype and Alleles ALL MDS MM NHL p-Value to CMV-Seropositive Controls p-Value to CMV-Seronegative Controls
Incidence
(%)
Incidence
(%)
Incidence
(%)
Incidence
(%)
rs4693608 AA 11 22 22 39.3 9 30 17 30.4 ALL: 0.66; 0.64 ALL: 0.12; 0.27
AG 28 56 22 39.3 17 56.7 27 48.2 MDS: 0.2; 0.22 MDS: 0.91; 0.65
GG 11 22 12 21.4 4 13.3 12 21.4 MM: 0.51; 0.39 MM: 0.24; 0.78
NHL: 0.92; 0.71 NHL: 0.62; 0.73
A 50 50 66 58.9 35 58.3 61 54.5
G 50 50 46 41.1 25 41.7 51 45.5
rs4693084 GG 28 58.3 41 75.9 16 59.3 35 64.8 ALL: 0.25; 0.21 ALL: 0.36; 0.26
GT 16 33.3 10 18.5 9 33.3 15 27.8 MDS: 0.12; 0.27 MDS: 0.16; 0.3
TT 4 8.3 3 5.6 2 7.4 4 7.4 MM: 0.54; 0.41 MM: 0.6; 0.44
NHL: 0.34; 0.65 NHL: 0.45; 0.69
G 72 75 92 85.2 41 75.9 85 78.7
T 24 25 16 14.8 13 24.1 23 21.3
rs4426765 AA 23 46.9 38 70.4 21 72.4 31 56.4 ALL: 0.034; 0.086 ALL: 0.008; 0.007
AC 17 34.7 10 18.5 7 24.1 20 36.4 MDS: 0.009; 0.14 MDS: 0.034; 0.79
CC 9 18.4 6 11.1 1 3.4 4 7.3 MM: 0.12; 0.054 MM: 0.51; 0.3
NHL: 0.85; 0.71 NHL: 0.65; 0.43
A 63 64.3 86 79.6 49 84.5 82 74.5
C 35 35.7 22 20.4 9 15.5 28 25.5
rs28649799 AA 42 85.7 49 89.1 23 79.3 50 89.3 ALL: 0.27; 0.75 ALL: 0.41; 0.75
AG 6 12.2 6 10.9 4 13.8 5 8.9 MDS: 0.43; 0.21 MDS: 0.26; 0.21
GG 1 2 0 0 2 6.9 1 1.8 MM: 0.003; 0.26 MM: 0.09; 0.26
NHL: 0.14; 0.32 NHL: 0.16; 0.32
A 90 91.8 104 94.5 50 86.2 105 93.75
G 8 8.2 6 5.5 8 13.8 7 6.25
rs4364254 TT 20 40 33 58.9 19 65.5 30 52.6 ALL: 0.89; 0.7 ALL: 0.084; 0.052
TC 22 44 19 33.9 6 20.7 21 36.8 MDS: 0.049; 0.015 MDS: 0.53; 0.5
CC 8 16 4 7.1 4 13.8 6 10.5 MM: 0.029; 0.071 MM: 0.056; 0.6
NHL: 0.3; 0.15 NHL: 0.5; 0.77
T 62 62 85 75.9 44 75.9 81 71.1
C 38 38 27 24.1 14 24.1 33 28.9

Significant deviations (p < 0.05) are marked in bold. The first p-value represents a correlation between genotypes and the second p-value marks a correlation between alleles.