Table 4.
SNP | Genotype and Alleles | ALL | MDS | MM | NHL | p-Value to CMV-Seropositive Controls | p-Value to CMV-Seronegative Controls | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
№ | Incidence (%) |
№ | Incidence (%) |
№ | Incidence (%) |
№ | Incidence (%) |
||||
rs4693608 | AA | 11 | 22 | 22 | 39.3 | 9 | 30 | 17 | 30.4 | ALL: 0.66; 0.64 | ALL: 0.12; 0.27 |
AG | 28 | 56 | 22 | 39.3 | 17 | 56.7 | 27 | 48.2 | MDS: 0.2; 0.22 | MDS: 0.91; 0.65 | |
GG | 11 | 22 | 12 | 21.4 | 4 | 13.3 | 12 | 21.4 | MM: 0.51; 0.39 | MM: 0.24; 0.78 | |
NHL: 0.92; 0.71 | NHL: 0.62; 0.73 | ||||||||||
A | 50 | 50 | 66 | 58.9 | 35 | 58.3 | 61 | 54.5 | |||
G | 50 | 50 | 46 | 41.1 | 25 | 41.7 | 51 | 45.5 | |||
rs4693084 | GG | 28 | 58.3 | 41 | 75.9 | 16 | 59.3 | 35 | 64.8 | ALL: 0.25; 0.21 | ALL: 0.36; 0.26 |
GT | 16 | 33.3 | 10 | 18.5 | 9 | 33.3 | 15 | 27.8 | MDS: 0.12; 0.27 | MDS: 0.16; 0.3 | |
TT | 4 | 8.3 | 3 | 5.6 | 2 | 7.4 | 4 | 7.4 | MM: 0.54; 0.41 | MM: 0.6; 0.44 | |
NHL: 0.34; 0.65 | NHL: 0.45; 0.69 | ||||||||||
G | 72 | 75 | 92 | 85.2 | 41 | 75.9 | 85 | 78.7 | |||
T | 24 | 25 | 16 | 14.8 | 13 | 24.1 | 23 | 21.3 | |||
rs4426765 | AA | 23 | 46.9 | 38 | 70.4 | 21 | 72.4 | 31 | 56.4 | ALL: 0.034; 0.086 | ALL: 0.008; 0.007 |
AC | 17 | 34.7 | 10 | 18.5 | 7 | 24.1 | 20 | 36.4 | MDS: 0.009; 0.14 | MDS: 0.034; 0.79 | |
CC | 9 | 18.4 | 6 | 11.1 | 1 | 3.4 | 4 | 7.3 | MM: 0.12; 0.054 | MM: 0.51; 0.3 | |
NHL: 0.85; 0.71 | NHL: 0.65; 0.43 | ||||||||||
A | 63 | 64.3 | 86 | 79.6 | 49 | 84.5 | 82 | 74.5 | |||
C | 35 | 35.7 | 22 | 20.4 | 9 | 15.5 | 28 | 25.5 | |||
rs28649799 | AA | 42 | 85.7 | 49 | 89.1 | 23 | 79.3 | 50 | 89.3 | ALL: 0.27; 0.75 | ALL: 0.41; 0.75 |
AG | 6 | 12.2 | 6 | 10.9 | 4 | 13.8 | 5 | 8.9 | MDS: 0.43; 0.21 | MDS: 0.26; 0.21 | |
GG | 1 | 2 | 0 | 0 | 2 | 6.9 | 1 | 1.8 | MM: 0.003; 0.26 | MM: 0.09; 0.26 | |
NHL: 0.14; 0.32 | NHL: 0.16; 0.32 | ||||||||||
A | 90 | 91.8 | 104 | 94.5 | 50 | 86.2 | 105 | 93.75 | |||
G | 8 | 8.2 | 6 | 5.5 | 8 | 13.8 | 7 | 6.25 | |||
rs4364254 | TT | 20 | 40 | 33 | 58.9 | 19 | 65.5 | 30 | 52.6 | ALL: 0.89; 0.7 | ALL: 0.084; 0.052 |
TC | 22 | 44 | 19 | 33.9 | 6 | 20.7 | 21 | 36.8 | MDS: 0.049; 0.015 | MDS: 0.53; 0.5 | |
CC | 8 | 16 | 4 | 7.1 | 4 | 13.8 | 6 | 10.5 | MM: 0.029; 0.071 | MM: 0.056; 0.6 | |
NHL: 0.3; 0.15 | NHL: 0.5; 0.77 | ||||||||||
T | 62 | 62 | 85 | 75.9 | 44 | 75.9 | 81 | 71.1 | |||
C | 38 | 38 | 27 | 24.1 | 14 | 24.1 | 33 | 28.9 |
Significant deviations (p < 0.05) are marked in bold. The first p-value represents a correlation between genotypes and the second p-value marks a correlation between alleles.