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. 2021 Dec 10;12(12):1977. doi: 10.3390/genes12121977

Table 4.

Differences in DAT1 and the NEO Five-Factor Inventory scale or the STAI scale, between healthy control subjects and NPS users.

STAI/NEO Five-Factor Inventory DAT1 ANOVA
NPS Users (n = 73) Control
(n = 301)
9/9
(n = 21)
9/10
(n = 138)
10/10
(n = 215)
Factor F (p-Value) ɳ2 Power (alfa = 0.05)
STAI state/scale 6.08 ± 2.23 4.69 ± 2.14 4.38 ± 2.25 5.05 ± 2.21 4.96 ± 2.24 intercept F1, 368 = 341.56 (p < 0.0001 *) 0.481 1.000
NPS users/control F1, 368 = 6.30 (p = 0.012 *) 0.017 0.707
DAT1 F2, 368 = 1.32 (p = 0.267) 0.007 0.285
NPS users/control × DAT1 F2, 368 = 1.23 (p = 0.291) 0.007 0.269
STAI trait/scale 7.34 ± 2.21 5.16 ± 2.18 5.00 ± 2.07 5.74 ± 2.36 5.54 ± 2.36 intercept F1, 368 = 457,68 (p < 0.0001 *) 0.554 1.000
NPS users/control F1, 368 = 15.07 (p = 0.0001 *) 0.039 0.972
DAT1 F2, 368 = 1.22 (p = 0.295) 0.007 0.266
NPS users/control × DAT1 F2,368 = 0.39 (p = 0.673) 0.002 0.114
Neuroticism/scale 6.92 ± 2.39 4.67 ± 2.01 4.48 ± 2.11 5.12 ± 2.36 5.16 ± 2.22 intercept F1, 368 = 415.23 (p < 0.0001 *) 0.530 1.000
NPS users/control F1, 368 = 14.02 (p = 0.0002 *) 0.037 0.962
DAT1 F2,36 8 = 2.62 (p = 0.073) 0.014 0.521
NPS users/control × DAT1 F2, 368 = 4.23 (p = 0.015 *) 0.022 0.739
Extraversion/scale 5.78 ± 2.16 6.37 ± 1.98 6.52 ± 2.06 6.19 ± 2.04 6.33 ± 2.01 intercept F1, 368 = 599.92 (p < 0.0001 *) 0.620 1.000
NPS users/control F1, 368 = 0.240 (p = 0.624) 0.001 0.078
DAT1 F2, 368 = 3.24 (p = 0.040 *) 0.017 0.615
NPS users/control × DAT1 F2, 368 = 3.81 (p = 0.023 *) 0.020 0.691
Openness/scale 4.84 ± 1.95 4.53 ± 1.61 4.29 ± 1.52 4.49 ± 1.78 4.68 ± 1.63 intercept F1, 368 = 409.43 (p < 0.0001 *) 0.527 1.000
NPS users/control F1, 368 = 0.055 (p = 0.814) 0.0001 0.056
DAT1 F2, 368 = 0.57 (p = 0.564) 0.003 0.145
NPS users/control × DAT1 F2, 368 = 0.14 (p = 0.872) 0.001 0.071
Agreeableness/scale 4.67 ± 2.06 5.60 ± 2.09 4.81 ± 1.63 5.30 ± 2.18 5.55 ± 2.10 intercept F1, 368 = 356,66 (p < 0.0001 *) 0.492 1.000
NPS users/control F1, 368 = 0.24 (p = 0.623) 0.001 0.078
DAT1 F2, 368 = 0.68 (p = 0.507) 0.004 0.164
NPS users/control × DAT1 F2, 368 = 1.15 (p = 0.314) 0.006 0.254
Conscientiousness/scale 5.82 ± 2.26 6.08 ± 2.15 6.62 ± 2.33 6.04 ± 2.10 5.96 ± 2.20 intercept F1, 368 = 452.91 (p < 0.0001 *) 0.552 1.000
NPS users/control F1, 368 = 0.20 (p = 0.654) 0.0005 0.073
DAT1 F2, 368 = 0.38 (p = 0.686) 0.002 0.111
NPS users/control × DAT1 F2, 368 = 0.44 (p = 0.638) 0.002 0.123

* Significant differences between groups.