Table 1.
Clinicodemographic characteristics of the study patients.
| Parameter | Value |
|---|---|
| Women | n = 485 (64.3%) |
| Mean (±SD) age (years) | 65.7 ± 12.09 |
| Age > 65 years | n = 415 (55.0%) |
| Median (range) duration of underlying disease (years) | 24 (0–70) |
| Underlying disease > 20 years | n = 392 (52.0%) |
| Median (range) duration of current ulcer (months) | 12 (1–504) |
| Duration of current ulcer > 12 months | n = 296 (39.3%) |
| Comorbidities | n = 647 (85.8%) |
| Rheumatoid arthritis | n = 118 (15.6%) |
| Arthritis | n = 234 (31.0%) |
| Diabetes mellitus | n = 160 (21.2%) |
| Atherosclerosis 1 | n = 96 (12.7%) |
| Cardiovascular disease 2 | n = 184 (24.4%) |
| Overweight/obesity (BMI ≥ 25 kg/m2) | n = 633 (84.0%) |
| Obesity (BMI ≥ 30 kg/m2) | n = 354 (46.9%) |
| Medial ulceration | n = 469 (62.2%) |
| Posterior ulceration | n = 121 (16.0%) |
| Anterior ulceration | n = 129 (17.1%) |
| Lateral ulceration | n = 216 (28.6%) |
| Circumferential ulceration | n = 24 (3.2%) |
| Posterior/circumferential ulceration | n = 141 (18.7%) |
| Ulcer locations ≥ 3 | n = 58 (7.7%) |
| Multiple ulcerations | n = 357 (47.3%) |
| Deep ulceration | n = 659 (87.4%) |
| Median (range) ulceration area at the baseline (cm2) | 8.25 (0.12–538) |
| Baseline ulceration area > 8.25 cm2 | n = 373 (49.5%) |
| Purulence/abscess | n = 40 (5.3%) |
| Unpleasant odor | n = 103 (13.7%) |
| Redness | n = 472 (62.6%) |
| Swelling | n = 124 (16.4%) |
| Warmth | n = 369 (48.9%) |
| Pain | n = 646 (85.7%) |
Notes: 1 Based on ABI values, patients with lower limb atherosclerosis were excluded from the study. 2 Patients with cardiac manifestations (according to NYHA or a history of myocardial infarction) and/or cerebral manifestations (a history of stroke/TIA). Abbreviations: BMI—body mass index; SD—standard deviation.