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. 2021 Dec 8;18(24):12965. doi: 10.3390/ijerph182412965

Table 2.

Odds ratios of culture-positive ulcers according to the clinicodemographic characteristics of the study patients; the results of univariate logistic regression analysis.

Variable Ulcer Culture OR (−) 95% CI (+) 95% CI p
Positive Negative
Age > 65 years 364 (87.7%) 272 (80.2%) 1.76 1.18 2.61 0.005
Female sex 419 (86.4%) 217 (80.7%) 1.52 1.02 2.27 0.039
Underlying disease > 20 years 330 (84.2%) 306 (84.5%) 0.97 0.66 1.44 0.896
Current ulcer > 12 months 270 (91.2%) 366 (79.9%) 2.61 1.64 4.15 <0.001
Rheumatoid arthritis 105 (89.0%) 531 (83.5%) 1.60 0.87 2.95 0.134
Arthritis 193 (82.8%) 443 (85.0%) 0.85 0.56 1.29 0.443
Diabetes mellitus 135 (84.4%) 501 (84.3%) 1.00 0.62 1.62 0.992
Atherosclerosis 72 (75.0%) 564 (85.7%) 0.50 0.30 0.83 0.008
Allergy 11 (73.3%) 625 (84.6%) 0.59 0.20 1.73 0.336
Cardiovascular disease 152 (82.6%) 484 (84.9%) 0.84 0.54 1.32 0.455
Kidney disease 6 (66.7%) 630 (84.6%) 0.37 0.09 1.48 0.158
Liver disease 4 (100.0%) 632 (84.3%) not applicable
Comorbidities 546 (84.4%) 90 (84.1%) 1.02 0.58 1.79 0.942
Multiple comorbidities 127 (78.9%) 509 (85.8%) 0.62 0.40 0.96 0.032
Overweight/obesity 538 (85.0%) 98 (81.0%) 1.33 0.80 2.20 0.268
Obesity 293 (82.8%) 343 (85.7%) 0.80 0.54 1.18 0.261
Medial ulceration 382 (83.4%) 246 (86.0%) 0.82 0.54 1.24 0.341
Posterior ulceration 105 (87.5%) 523 (83.8%) 1.35 0.76 2.42 0.31
Anterior ulceration 112 (87.5%) 516 (83.8%) 1.36 0.77 2.39 0.291
Lateral ulceration 188 (87.0%) 440 (83.3%) 1.34 0.85 2.12 0.207
Circumferential ulceration 22 (91.7%) 606 (84.2%) 2.07 0.48 8.92 0.329
Deep ulceration 564 (85.6%) 64 (75.3%) 1.95 1.14 3.34 0.015
Multiple ulcers 309 (86.8%) 325 (82.1%) 1.44 0.96 2.14 0.076
Purulence/abscess 40 (100.0%) 596 (83.5%) not applicable
Unpleasant odor 103 (100.0%) 533 (81.9%) not applicable
Redness 404 (85.6%) 230 (82.1%) 1.29 0.87 1.93 0.209
Swelling 115 (92.7%) 521 (82.7%) 2.67 1.32 5.43 0.007
Warmth 313 (84.8%) 321 (83.8%) 1.08 0.73 1.60 0.703
Pain 545 (84.5%) 90 (83.3%) 1.10 0.64 1.90 0.722
Ulceration area > 8.25 cm2 331 (88.7%) 305 (80.0%) 1.96 1.31 2.95 0.001

Abbreviations: OR—odds ratio; 95% CI—95% confidence interval.