Skip to main content
. 2021 Dec 6;12(12):1953. doi: 10.3390/genes12121953

Figure 4.

Figure 4

MRI markers of small vessel disease in three CADASIL patients: Patient 1 (a–d) severe leukoaraiosis involving subcortical white matter, external capsule and periventricular regions in a symmetrical pattern on axial FLAIR (a,b) MRI, associated with deel and lobar supratentorial microbleeds on SWI (axial MiP sequences) MRI (c) and enlarged perivascular spaces in the basal ganglia on coronal T2W (d) MRI. Patient 2 (e,f) anterior temporal lobe involvement (e) and periventricular and iuxtacortical white matter hyperintensities (f) on axial FLAIR MRI. Patient 3 (g–j) recent subcortical ischemic stroke on the right portion of the pons on FLAIR (g) and DWI (h) MRI sequences, supratentorial white matter hyperintensities with a dotted distribution involving the external capsule and the periventricular regions on axial FLAIR (i) MRI and multiple supratentorial deep and lobar microbleeds on SWI (MiP sequences) MRI (j).