Table 4.
Biopharmaceutical Parameter | Formulations | Statistic | ||
---|---|---|---|---|
CSP-CTS Hydrogel 1 | CSP-P407 Hydrogel 2 | CTS/P407 Hydrogel 3 | p < 0.05 | |
J (μg/h) | 36.76 ± 0.31 | 21.08 ± 4.98 | 31.84 ± 2.76 | 1 vs. 2 2 vs. 3 |
Kp × 104 (cm/h) | 7.24 ± 0.06 | 4.15 ± 0.98 | 6.27 ± 0.54 | 1 vs. 2 2 vs. 3 |
Css (μg/mL) | 1.65 ± 0.01 | 0.95 ± 0.22 | 1.43 ± 0.12 | 1 vs. 2 2 vs. 3 |
Qr (µg/cm2) | 156.23 ± 14.91 | 118.51 ± 12.78 | 409.40 ± 48.34 | 1 vs. 3 2 vs. 3 |