Date	Event	Description
6 October 2016	Amended	Please note: This protocol template refers to the Cochrane Metabolic and Endocrine Disorders (CMED) Group and the official Cochrane MECIR (Methodological Expectations of Cochrane Intervention Reviews) standards (standards for the conductandstandards for the reportingof Cochrane intervention reviews) ‐ see 'Guidance' pane Please do not forget to check on your protocol draft with the help of the protocol submission form before checking in your finalprotocol draft for editorial approval! No standard items, appendices or title of this protocol template may be deleted without prior approval of the CMED Group!