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. 2021 Dec 7;18(24):12903. doi: 10.3390/ijerph182412903

Table 10.

Determinants and multinomial logistic regression analysis demonstrating factors associated with hesitance and refusal of a COVID-19 vaccine.

Variables Hesitated Will Not Be Vaccinated
cOR (95% CI) p-Value aOR a (95% CI) p-Value cOR (95% CI) p-Value aOR a (95% CI) p-Value
Age group
18–29 3.26 (2.46–4.32) <0.0001 1.79 (1.04–3.08) 0.035 5.46 (3.17–9.41) <0.0001 1.90 (0.62–5.79) 0.261
30–39 2.00 (1.50–2.67) <0.0001 1.43 (0.81–2.51) 0.216 2.63 (1.49–4.65) 0.001 0.76 (0.22–2.64) 0.661
40–49 1.21 (0.89–1.65) 0.231 1.14 (0.63–2.08) 0.666 1.68 (0.91–3.08) 0.095 0.65 (0.16–2.62) 0.542
50+ ref ref ref ref
Gender
Male 1.08 (0.87–1.34) 0.499 0.83 (0.60–1.16) 0.281 0.88 (0.60–1.29) 0.505 0.71 (0.35–1.41) 0.321
Female ref ref ref ref
Residence
Rural 3.04 (2.50–3.71) <0.0001 1.83 (1.32–2.53) 0.000 2.67 (1.94–3.66) <0.0001 3.25 (1.77–5.96) <0.0001
Urban ref ref ref ref
Other vaccines
Do not accept at all 13.17 (3.68–47.14) <0.0001 4.17 (1.07–16.22) 0.039 193.75 (46.62–805.17) <0.0001 24.34 (4.84–122.36) <0.0001
Do not trust most of the vaccines and refuse 10.42 (4.36–24.90) <0.0001 4.05 (1.58–10.40) 0.004 33.21 (9.08–121.48) <0.0001 10.25 (2.36–44.49) 0.002
Accept vaccines, but refuses sometimes 3.33 (2.33–4.76) <0.0001 1.49 (0.98–2.28) 0.072 8.24 (3.52–19.32) <0.0001 4.68 (1.75–12.47) 0.002
Accept all vaccines, but do not completely trust 3.79 (2.74–5.25) <0.0001 1.82 (1.23–2.66) 0.003 5.27 (2.22–12.52) <0.0001 3.49 (1.31–9.31) 0.012
Accept all vaccines ref ref ref ref
Vaccine importance
I don’t know 8.96 (4.67–17.19) <0.0001 5.72 (2.81–11.67) <0.0001 48.41 (18.79–124.78) <0.0001 13.30 (4.32–40.94) <0.0001
Unimportant 5.93 (2.06–17.11) 0.001 4.50 (1.47–13.76) 0.008 31.85 (8.18–123.96) <0.0001 10.08 (1.90–53.37) 0.007
Somewhat important 6.09 (4.50–8.24) <0.0001 4.81 (3.38–6.84) <0.0001 7.25 (3.39–15.49) <0.0001 5.06 (2.12–12.10) <0.0001
Very important ref ref ref ref
Source of information
Friends/Family/ Colleagues 1.34 (0.56–3.25) 0.510 5.27 (0.74–37.74) 0.095 5.61 (2.34–13.43) <0.0001 35.88 (3.42–376.50) 0.003
TV/Radio/ Newspaper 1.78 (1.02–3.11) 0.043 1.39 (0.61–3.13) 0.419 5.52 (2.93–10.40) <0.0001 5.34 (1.77–16.09) 0.003
Social media/Websites 1.76 (1.18–2.63) 0.005 2.11 (1.03–4.33) 0.043 1.94 (1.02–3.72) 0.044 1.68 (0.44–6.36) 0.446
Official source ref ref ref ref
Education
Primary 1.88 (0.59–5.99) 0.287 2.28 (0.59–8.79) 0.233 9.31 (2.37–36.66) 0.001 7.57 (1.27–45.17) 0.026
Secondary 1.02 (0.77–1.36) 0.889 1.09 (0.77–1.54) 0.624 1.86 (1.05–3.27) 0.032 3.08 (1.13–8.41) 0.028
College 0.72 (0.42–1.21) 0.209 0.91 (0.49–1.67) 0.749 2.07 (0.89–4.82) 0.092 1.41 (0.70–2.82) 0.732
Graduate ref ref ref ref

cOR, crude odds ratio; aOR, adjusted odds ratio; CI, confidence interval; Ref, reference value. a Adjusted for age, gender, and education.