. 2021 Nov 29;12(12):1929. doi: 10.3390/genes12121929

Table 3.

Modified miRNAs in MCC.

Nr	Ref	Expression	miRNA	Probe	Species	Role
1	Ning et al. [73]	upregulated	miRNA-9 miRNA-502-3p miRNA-7 miRNA-340 miRNA-182 miRNA-190b miRNA-873 miRNA-183	tissue	human	increasing tumor motility and colony formation. Potential diagnostic and therapeutic applications in cases of MCPyV-positive MCC
1	Ning et al. [73]	downregulated	miRNA-3170 miRNA-125b miRNA-374c	tissue	human	not mentioned
2	Renwick et al. [74]	upregulated	miRNA-205 miRNA-375	tissue	human	microRNAs downregulate the expression of gene targets through interaction with their three prime untranslated region (3′ UTR). miRNA-375 targets MTPN(myotrophin) gene, which encodes the myotrophin protein, further regulating hormone release and exocytosis. Potential diagnostic role by discerning BCC from MCC
3	Veija et al. [76]	downregulated	miR-34a, miR-1539, miR-30a, miR-142-3p	tissue	human	may play a role in the oncogenesis of MCV-negative tumors.
3	Veija et al. [76]	upregulated	miR-181d	tissue	human	may play a role in the oncogenesis of MCV-negative tumors.