AD	Alzheimer’s disease
ADRD	Alzheimer’s disease and related dementias
ALIS	Automated ligand identification system
APP	Amyloid–β precursor protein
AS	Antisense transcript
ASO	Antisense oligonucleotide
BACE1-AS	β-secretase 1 antisense transcript
BBB	Blood–brain barrier
BDNF	Brain-derived neurotropic factor
Cat-ELCCA	Catalytic enzyme-linked click chemistry assay
CDR1-AS	Cerebellar degeneration-related protein 1 antisense RNA
Chem-CLIP-Map-Seq	Chemical Cross-Linking and Isolation by Pull-down to Map Small Molecule-RNA Binding Sites
ChIP-seq	Chromatin immunoprecipitation-RNA-seq
circRNA	Circular RNA
CREB	cAMP response element-binding protein
DGCR8	DiGeorge critical region 8
DRUG-seq	Digital RNA with perturbation of Genes
ENCODE	Encyclopedia of DNA Elements
Exp5	Exportin 5
FANTOM	Functional Annotation of the Mammalian Genome
FDA	Food and Drug Administration
FID	Fluorescent indicator displacement
FP	Fluorescence polarization
FRET	Fluorescence resonance energy transfer
FTD	Frontotemporal dementia
HD	Huntington’s disease
HOTAIR	HOX antisense intergenic RNA
HTS	High-throughput screen
HTT	Huntingtin
ITC	Isothermal titration calorimetry
LBD	Lewy body dementia
LC-MS	Liquid chromatography-mass spectrometry
lncRNA	Long non-coding RNA
MALAT1	Metastasis-associated lung adenocarcinoma transcript 1
MED	Multiple etiology dementias
miRNA	MicroRNA
MoA	Mechanism of action
mRNA	Messenger RNA
ncRNA	Non-coding RNA
NMR	Nuclear magnetic resonance
PAIN	Pan-assay interference
PDB	Protein data bank
PK/PD	Pharmacokinetics and pharmacodynamics
PRC2	Polycomb repressive complex 2
PSEN1	Presenilin 1
PSEN2	Presenilin 2
RBP	RNA binding protein
REST	RE1-silencing transcription factor
RISC	RNA-induced silencing complex
rRNA	Ribosomal RNA
shRNA	Short hairpin RNA
siRNA	Small interfering RNA
SMN2	Survival of motor neuron 2
sncRNA	Small ncRNA
snoRNA	Small nucleolar RNA
snRNA	Small nuclear RNA
SPR	Surface plasmon resonance
TORNADO-seq	Targeted organoid sequencing
TRBP	Transactivating response RNA-binding protein
tRNA	Transfer RNA
VCID	Vascular contributions to cognitive impairment and dementia