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. 2021 Dec 23;100(51):e28315. doi: 10.1097/MD.0000000000028315

Table 2.

Drug resistance mutations detected in screening samples.

Mutations
Sample Subtype Protease NRTI NNRTI Integrase
5.ph17 CRF01_AE None None V90I
6.ph17 CRF01_AE L10F; L10V None E138G
10.ph17 B L10V None none
11.ph17 CRF01_AE M46L None none
17.ph17 CRF01_AE None D67N; K70R; M184V; T215F; T215I; T215S A98G, G190A
21.ph17 B M46L; A71V None K101Q;E138K
27.ph17 CRF01_AE None None E138A
28.ph17 CRF01_AE None None V106I none
39.ph17 CRF01_AE None K65R; K70T; L74I; M184I V90I; K103N; V108I; Y181C; M230L
2.ph18∗ B L10I None V179D
17.ph18 B L10V None none
18.ph18 CRF01_AE None None V90I, V106I, E138G
32.ph18∗ CRF01_AE None Y115F; T215Y Y188C; G190V
34.ph18 B A71V; L90M None Y181C, H221Y
1.ph19 CRF01_AE None None V106I

Mutations associated with protease, reverse transcriptase (nucleoside – NRTI and non-nucleoside – NNRTI) and integrase inhibitors.

Subtype listed in the Stanford HIV Drug Resistance designation for Protease-RT FASTA submitted for that sample.

Bolded = treatment experienced, failing ART.

∗ Partners w/ another patient in the cohort.