Figure 1.
Three categories of off-target activities. (a) The situation of base mismatch between guide RNA and target sequence. (b) The situation of base deficiency on guide RNA. (c) The situation of base insertion on guide RNA.
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.