Table 5.
Effects of FRJ on gene expression of mechanical barrier of colon.
Group | ZO-1 | Claudin-1 | Claudin-4 | Occludin | E-cadherin | Muc-2 |
---|---|---|---|---|---|---|
C | 1.00 ± 0.00 a | 1.00 ± 0.00 a | 1.00 ± 0.00 a | 1.00 ± 0.00 a | 1.00 ± 0.00 a | 1.00 ± 0.00 a |
L | 1.41 ± 0.13 b | 1.31 ± 0.13 b | 1.30 ± 0.06 b | 1.13 ± 0.08 b | 1.19 ± 0.09 b | 1.49 ± 0.21 b |
M | 1.82 ± 0.06 c | 1.48 ± 0.13 c | 1.43 ± 0.08 c | 1.33 ± 0.11 c | 1.35 ± 0.24 b | 1.82 ± 0.33 c |
H | 1.58 ± 0.10 bc | 1.61 ± 0.04 d | 1.42 ± 0.12 c | 1.32 ± 0.05 c | 1.30 ± 0.07 b | 1.67 ± 0.18 bc |
C: mice fed with standard diet; L: mice fed with 3% (wt:wt) FRJ supplementation; M: mice fed with 6% (wt:wt) FRJ supplementation; H: mice fed with 9% (wt:wt) FRJ supplementation. Different letters indicated significantly different at p < 0.05.