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. Author manuscript; available in PMC: 2023 Feb 1.
Published in final edited form as: Pharmacogenet Genomics. 2022 Feb 1;32(2):51–59. doi: 10.1097/FPC.0000000000000452

Table 4. Whether Routine Screening for Genetic Biomarkers was Recommended by Therapeutic Area.

Counts represent instances wherein guidance sources recommended genetic screening in all patients being prescribed the applicable medication. CPIC guidelines were not included since they do not address whether genetic testing should be ordered.

Therapeutic Area Recommendation for Routine Screening
Overall FDA CPG
Oncology 137 (64.0%) 60 (50.4%) 77 (81.1%)
Hematology 35 (46.1%) 17 (38.6%) 18 (56.3%)
Psychiatry 2 (4.3%) 2 (5.4%) 0 (0%)
Cardiovascular 0 (0%) 0 (0%) 0 (0%)
Anesthetics 0 (0%) 0 (0%) 0 (0%)
Neurology 8 (28.6%) 8 (30.8%) 0 (0%)
Antivirals 3 (15.0%) 1 (6.3%) 2 (50.0%)
Anti-Infectives 4 (23.5%) 2 (14.3%) 2 (66.7%)
Gastroenterology 3 (17.6%) 3 (17.6%) N/A
All Other TAs 14 (23.3%) 9 (16.4%) 5 (100%)
Total 206 (38.2%) 102 (27.8%) 104 (60.5%)

All data are presented as follows: counts (percentages). “All Other TAs” include pulmonary, rheumatology, endocrinology, analgesic, urology, immunosuppressant, medical countermeasure, metabolism, reproduction, addiction, and bone products.

Abbreviations: CPG = Clinical Practice Guidelines from U.S. Professional Organizations; CPIC = Clinical Pharmacogenetics Implementation Consortium; FDA = U.S. Food and Drug Administration; N/A = not applicable, indicates that no recommendations were provided by the designated source