Fig. 6.

Systemic inflammation in recipients post-HTx. Changes in plasma a total white blood cells (WBC, 10⁹/L); b big endothelin-1 (BET-1, pg/mL); c interleukin 1β (pg/mL); d interleukin-6 (pg/mL); e interleukin-8 (pg/mL); f interleukin-10 (pg/mL); and g TNFα (ng/mL) following confirmation of donor BSD (or sham). Data are expressed as mean ± SEM, n = 4/group. Top F and p values on each graph represent effect of time, and bottom F and p values represent differences between BSD vs. sham over time. B Baseline, ST stabilisation 1 h following completion of instrumentation procedures in recipient, 0H—successful weaning from CPB. Dotted lines on c and g represent the lowest detectable limit of the respective cytokine ELISA