Skip to main content
. 2021 Dec 10;8:777098. doi: 10.3389/fcvm.2021.777098

Figure 5.

Figure 5

SLC37A2 deficiency promotes oxidized LDL (OxLDL)-induced macrophage inflammation in vitro. (A) SLC37A2 protein expression analyzed by Western blotting in WT and Slc37a2−/− bone marrow-derived macrophages (BMDMs) treated with 50 μg/ml oxLDL for 0-24 h. (B) Quantification of cellar total cholesterol (TC), free cholesterol (FC), and cholesterol ester (CE) in WT and Slc37a2−/− BMDMs after treated with or without 25 or 50 μg/ml oxLDL for 24 h. (C) Relative transcript level of cytokines in WT and Slc37a2−/− BMDMs stimulated with 50 μg/ml oxLDL for 0-24 h, measured by qPCR. Data are representative of two independent experiments with three samples per group (mean ± SEM). *p < 0.05; unpaired, two-tailed Student's t-test.