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. 2021 Dec 10;8:649759. doi: 10.3389/fmed.2021.649759

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Copyright © 2021 Nishida, Hosomi, Fujimoto, Nakata, Sugita, Itani, Nadatani, Fukunaga, Otani, Tanaka, Nagami, Taira, Kamata, Watanabe, Ohfuji and Fujiwara.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparison of disease activity before and during lockdown. (A) Ulcerative colitis (UC). (B) Crohn's disease (CD). Disease activity in UC changed as follows: remission, 213 (88.4%); mild activity, 14 (5.8%); moderate activity, 11 (4.6%); severe activity, 3 (1.2%) to remission, 180 (74.7%); mild activity, 29 (12.0%); moderate activity, 22 (9.1%); severe activity, 10 (4.1%). Disease activity in CD changed as follows: remission, 123 (58.6%); mild activity, 46 (21.9%); moderate activity, 39 (18.6%); severe activity, 2 (1.0%) to remission, 96 (45.7%); mild activity, 53 (25.2%); moderate activity, 54 (25.7%); severe activity, 2 (1.0%).