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. 2021 Dec 10;12:796565. doi: 10.3389/fphar.2021.796565

FIGURE 1.

FIGURE 1

Effect of curcumin on the morphology and cell apoptosis of the retinas in diabetic rats after 4 weeks treatment. Representative images of (A) H&E-stained sections (bar = 50 µm) and (B) TUNEL-stained sections (bar = 50 µm) of the retinal tissues among different groups; (C) The thickness of the overall retina in different groups; (D) The mean ratios of TUNEL positive cells of the rat retinas among different groups. CON, control group; DM, STZ-induced diabetic model group; CUR, 200 mg/kg curcumin treatment group; INS, long-acting insulin treatment group; CUR + INS, 200 mg/kg curcumin and long-acting insulin treatment group; GCL, ganglion cell layer; INL, inner nuclear layer; ONL, outer nuclear layer. All data are expressed as the mean ± standard deviation (n > 3). ** p < 0.01 vs. the CON group; ## p < 0.01 vs. the DM group.