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. 2021 Dec 10;12:796565. doi: 10.3389/fphar.2021.796565

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Copyright © 2021 Xie, Chen, Chen, Huang, Peng, Tian, Wu and Huang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of treatment on the relative protein expression levels of p62 and LC3B-Ⅱ in the retina of rats. (A) Representative immunoblots of p62 and LC3B-Ⅱ in retinas of rats among different groups. (B) Quantification of immunoblots of p62 and LC3B-Ⅱ, β-actin used as the loading control. CON, control group; DM, STZ-induced diabetic model group; CUR, 200 mg/kg curcumin treatment group; INS, long-acting insulin treatment group; CUR + INS, 200 mg/kg curcumin and long-acting insulin treatment group. All data are expressed as the mean ± standard deviation (n > 3). ^** p < 0.01 vs. the CON group; ^## p < 0.01 vs. the DM group; ^&& p < 0.01 vs. the CUR group.