TABLE 1.
Effects of treatment on fasting blood glucose and body weight in experimental animals.
| Group | Fasting blood glucose (mmol·L−1) | Fasting body weight (g) | ||||
|---|---|---|---|---|---|---|
| Initial | 72 h | 4 weeks | Initial | 72 h | 4 weeks | |
| CON | 4.5 ± 0.4 | 4.3 ± 0.4 | 5.5 ± 0.6 | 230.8 ± 10.0 | 267.8 ± 16.6 | 412.8 ± 23.8 |
| DM | 4.4 ± 0.5 | 30.2 ± 3.8** | 23.3 ± 4.2** | 246.7 ± 9.4 | 257.5 ± 25.1 | 298.5 ± 60.0** |
| CUR | 4.6 ± 0.5 | 24.9 ± 5.3** | 13.5 ± 8.2## | 249.5 ± 9.7 | 262.5 ± 12.8 | 315.0 ± 45.0** |
| INS | 4.3 ± 0.6 | 27.2 ± 5.7** | 7.2 ± 2.1## | 249.0 ± 10.4 | 258.0 ± 11.5 | 381.5 ± 14.9##, && |
| CUR + INS | 4.5 ± 0.5 | 25.5 ± 7.3** | 7.8 ± 2.8## | 245.0 ± 14.6 | 254.2 ± 11.3 | 349.8 ± 55.0##, & |
CON, control group; DM, STZ-induced diabetic model group; CUR, 200 mg/kg curcumin treatment group; INS, long-acting insulin treatment group; CUR + INS, 200 mg/kg curcumin and long-acting insulin treatment group. All data are expressed as the mean ± standard deviation (n = 3). ** p < 0.01 vs. the CON group; ## p < 0.01 vs. the DM group; && p < 0.01 vs. the CUR group; & p < 0.05 vs. the CUR group.