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. 2021 Dec 10;12:796565. doi: 10.3389/fphar.2021.796565

TABLE 2.

Effects of treatment on retinal superoxide dismutase, malondialdehyde, and glutathione content of homogenate of retinal tissues.

Group SOD (U·g−1) MDA (nmol·g−1) T-GSH (µmol·L−1) GSSG/GSH
CON 47.19 ± 3.3 35.56 ± 0.8 2.97 ± 0.7 0.96 ± 0.0
DM 30.99 ± 2.9** 54.93 ± 0.4** 1.31 ± 0.1** 1.31 ± 0.0**
CUR 26.88 ± 2.1**, ## 31.57 ± 0.7**, ## 1.04 ± 0.1**, ## 1.52 ± 0.1**, ##
INS 61.10 ± 2.5**, ##, && 36.30 ± 0.6##, && 2.90 ± 0.0##, && 0.97 ± 0.0##, &&
CUR + INS 41.27 ± 1.7**, ##, && 35.94 ± 1.2##, && 1.91 ± 0.0**, ##, && 1.10 ± 0.0##, &&

CON, control group; DM, STZ-induced diabetic model group; CUR, 200 mg/kg curcumin treatment group; INS, long-acting insulin treatment group; CUR + INS, 200 mg/kg curcumin and long-acting insulin treatment group; SOD, superoxide dismutase; MDA, malondialdehyde T-GSH, total glutathione; GSSG, oxidized glutathione; GSH, reduced glutathione. All data are expressed as the mean ± standard deviation (n = 3). ** p < 0.01 vs. the CON group; ## p < 0.01 vs. the DM group; && p < 0.01 vs. the CUR group.