TABLE 2.
Group | SOD (U·g−1) | MDA (nmol·g−1) | T-GSH (µmol·L−1) | GSSG/GSH |
---|---|---|---|---|
CON | 47.19 ± 3.3 | 35.56 ± 0.8 | 2.97 ± 0.7 | 0.96 ± 0.0 |
DM | 30.99 ± 2.9** | 54.93 ± 0.4** | 1.31 ± 0.1** | 1.31 ± 0.0** |
CUR | 26.88 ± 2.1**, ## | 31.57 ± 0.7**, ## | 1.04 ± 0.1**, ## | 1.52 ± 0.1**, ## |
INS | 61.10 ± 2.5**, ##, && | 36.30 ± 0.6##, && | 2.90 ± 0.0##, && | 0.97 ± 0.0##, && |
CUR + INS | 41.27 ± 1.7**, ##, && | 35.94 ± 1.2##, && | 1.91 ± 0.0**, ##, && | 1.10 ± 0.0##, && |
CON, control group; DM, STZ-induced diabetic model group; CUR, 200 mg/kg curcumin treatment group; INS, long-acting insulin treatment group; CUR + INS, 200 mg/kg curcumin and long-acting insulin treatment group; SOD, superoxide dismutase; MDA, malondialdehyde T-GSH, total glutathione; GSSG, oxidized glutathione; GSH, reduced glutathione. All data are expressed as the mean ± standard deviation (n = 3). ** p < 0.01 vs. the CON group; ## p < 0.01 vs. the DM group; && p < 0.01 vs. the CUR group.