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. 2021 Dec 10;15:787475. doi: 10.3389/fnbeh.2021.787475

Figure 2.

Figure 2

Animals exhibit anxiolytic behavior 2- and 52-weeks following injury. (A) Representative heat map images show that blast animals spent more time in the enclosed arm (outlined area) than their sham counterparts. (B) Blast animals spent significantly more time within the enclosed arm than the open arm of the EPM 2 weeks following injury. There was no significant preference for the central zone of the arena. (C) Similarly, 52 weeks following repeated blast exposure, data shows that blast animals spent more time within the enclosed arm than the open arm of the EPM. No significant preference for the central zone was observed for either blast or sham animals. *p < 0.05,***p < 0.001,****p < 0.0001, Data is represented as Mean ± SEM. EPM, Elevated Plus Maze.